Haybaeck J. (Ed.) Mechanisms of Molecular Carcinogenesis. Volume 1

Springer International Publishing AG, 2017. — 302 p. — ISBN: 978-3-319-53657-6.Divided into two volumes the work offers a so far unmatched broad and at the same time deep knowledge on molecular and cellular mechanisms of carcinogenesis and offers comprehensive insight into clinical, therapeutic and technological aspects. This 1st Volume presents tumor entities of the ocular system, the thyroid organ, the oesophagus, gliomas, non-glial brain tumors, head and neck as well as lung cancer.
In addition it also discusses in-depth potential novel molecular players and the role of stem cells as well as the endocannabinoid system in carcinogenesis, it furthermore explains tumor metabolism components and signaling pathways. Each of the chapters discusses potential therapeutic strategies and novel drug targets.
The book addresses basic scientists and medical researchers interested in translational cancer research.The Endocannabinoid System in Carcinogenesis
MACC1, a Novel Player in Solid Cancer Carcinogenesis
Axl and Its Mediated Signaling Axis in Cancer
Insulin Signaling Linking Metabolism and Malignancy
Translational Control and mTOR in Cancer
NF-κB and Its Implication in Liver Health and Cancer Development
Molecular Carcinogenesis of Glial Brain Tumors
Molecular Carcinogenesis of Non-glial Brain Tumors
Molecular Carcinogenesis of Uveal Melanoma
Molecular Aspects of Thyroid Carcinogenesis
Carcinogenesis in the Epithelium of the Upper Aerodigestive Tract
Carcinogenesis of Sinonasal Carcinomas
Parotid Cancer
Carcinogenesis of Laryngeal Tumors
Photodynamic Therapy for Esophageal Cancer: Functional, Clinical, and Immunological Aspects
Biomarkers for Predicting Neoplastic Progression in Barrett’s Esophagus
The Role of Macrophages Within Microenvironment in a Lung Cancer Development and Progression
Progression of Lung Cancer: Role of Hypoxia and the Metabolic Tumor Microenvironment