Jameson J.L. (ed.) Hormone Resistance Syndromes

New York: Humana Press, 1999. — 285 p.In Hormone Resistance Syndromes, leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. In addition to helping discover additional resistance syndromes, readers are afforded a unique opportunity to understand hormone action in normal physiology.
Timely and authoritative, Hormone Resistance Syndromes provides an insightful survey of this critical area, one that will serve as a gold-standard reference for all those clinicians and researchers actively studying these mutations today.Front Matter
Dwarfism
Laron Syndrome
Pseudohypoparathyroidism
Hereditary Resistance to Vitamin D
Decreased Responsiveness to Extracellular Ca 2+ Owing to Abnormalities in the Ca 2+ o -Sensing Receptor
Resistance to TSH
Thyroid Hormone Resistance
Diabetes Mellitus
LH Insensitivity Syndrome
FSH Resistance
Genetic Alterations of Androgen Receptor Function
Retained Müllerian Ducts
Adrenal Insufficiency
Glucocorticoid Resistance and Hypersensitivity
Back Matter